"Database of Curated Mutations (DoCM)"[submitter] AND "RET"[gene] - ClinVar - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 18

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 13933	NM_020975.6(RET):c.1826G>A (p.Cys609Tyr)	RET (C609Y +12 more)	Single nucleotide variant (missense variant)	not provided +6 more	GPathogenic
Select item 376312	NM_020975.6(RET):c.1834_1860del (p.Phe612_Cys620del)	RET	Deletion (inframe_indel +1 more)	Medullary thyroid carcinoma	GLikely pathogenic
Select item 13929	NM_020975.6(RET):c.1852T>C (p.Cys618Arg)	RET (C618R +12 more)	Single nucleotide variant (missense variant)	not provided +4 more	GPathogenic
Select item 24901	NM_020975.6(RET):c.1853G>A (p.Cys618Tyr)	RET (C364Y +11 more)	Single nucleotide variant (missense variant)	not provided +2 more	GPathogenic
Select item 13916	NM_020975.6(RET):c.1859G>A (p.Cys620Tyr)	RET (C620Y +12 more)	Single nucleotide variant (missense variant)	Multiple endocrine neoplasia, type 2 +2 more	GPathogenic
Select item 24908	NM_020975.6(RET):c.1888T>C (p.Cys630Arg)	RET (C376R +13 more)	Single nucleotide variant (missense variant)	Multiple endocrine neoplasia, type 2	GPathogenic
Select item 24916	NM_020975.6(RET):c.1892A>G (p.Asp631Gly)	RET (D631G +14 more)	Single nucleotide variant (missense variant)	Medullary thyroid carcinoma	GLikely pathogenic
Select item 376313	NM_020975.6(RET):c.1894_1899del (p.Glu632_Leu633del)	RET	Deletion (inframe_indel +1 more)	Multiple endocrine neoplasia, type 2	GUncertain significance
Select item 13917	NM_020975.6(RET):c.1900T>C (p.Cys634Arg)	RET (C634R +14 more)	Single nucleotide variant (missense variant)	Thyroid gland carcinoma +5 more	GPathogenic/Likely pathogenic
Select item 13909	NM_020975.6(RET):c.1901G>A (p.Cys634Tyr)	RET (C634Y +14 more)	Single nucleotide variant (missense variant)	not provided +5 more	GPathogenic
Select item 13918	NM_020975.6(RET):c.1902C>G (p.Cys634Trp)	RET (C634W +14 more)	Single nucleotide variant (missense variant)	not provided +3 more	GPathogenic
Select item 13931	NM_020975.6(RET):c.2304G>C (p.Glu768Asp)	RET (E768D +17 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GPathogenic
Select item 13936	NM_020975.6(RET):c.2372A>T (p.Tyr791Phe)	RET (Y791F +17 more)	Single nucleotide variant (missense variant)	not specified +9 more	GBenign/Likely benign
Select item 38613	NM_020975.6(RET):c.2410G>C (p.Val804Leu)	RET (V804L +17 more)	Single nucleotide variant (missense variant)	MEN2 phenotype: Unclassified +4 more	GPathogenic/Likely pathogenic
Select item 38629	NM_020975.6(RET):c.2647_2648delinsTT (p.Ala883Phe)	RET (A883F +17 more)	Indel (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GPathogenic/Likely pathogenic
Select item 13951	NM_020975.6(RET):c.2671T>G (p.Ser891Ala)	RET (S891A +17 more)	Single nucleotide variant (missense variant)	not provided +10 more	GPathogenic
Select item 376314	NM_020975.6(RET):c.2694_2705del (p.Asp898_Glu901del)	RET	Deletion (inframe_indel +1 more)	Hereditary cancer-predisposing syndrome	GUncertain significance
Select item 13919	NM_020975.6(RET):c.2753T>C (p.Met918Thr)	RET (M918T +17 more)	Single nucleotide variant (missense variant)	Familial medullary thyroid carcinoma +17 more	GPathogenic/Likely pathogenic